Cracking the Code of PATM

People Allergic to Me (PATM) condition has long baffled sufferers and medical experts, leaving many without a diagnosis and grappling with mental health challenges. Even though there are some shared microbes in the microbiome, only small subset of PATM sufferers have received a TMAU diagnosis. 

A study conducted by Professor Sekine and published in Nature Scientific Reports has uncovered new insights into this condition. Sekine's research team comprehensively analyzed the skin gas profiles of 44 study participants, 20 of whom suffered from PATM while 24 were in a control group. Using gas chromatography mass spectrometry, they identified major differences in the production of volatile organic compounds between the two groups.

Among the 75 measured skin gases, the PATM group exhibited significantly greater emission fluxes for some chemicals with offensive odors. The emissions of several petrochemicals were also notably higher in the PATM group aligning with our yet to be published results from MEBO-Menssana Alveolar Breath Test Study (registered as NCT03451994). Results of our Microbiome study (registered as NCT03582826) may explain possible microbial sources of compounds that differentiate PATM from non-PATM populations. More on Professor Sekine's findings is available in Aurametrix blog and the original paper. 

We will be publishing our complementary results soon, further contributing to the scientific community's knowledge of PATM, TMAU and MEBO.

 

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